Our suggested program length is 3-5 years. A significant amount of research has shown that although symptom reduction typically happens well within the first year, you are likely to receive long-term results (at least 7 years of overall remission) if you continue the treatment for at least 3 years.
Articles/Studies for Reference
Pfaar O, Bachert C, Kuna P, et al. Sublingual allergen immunotherapy with a liquid birch pollen product in patients with seasonal allergic rhinoconjunctivitis with or without asthma. J Allergy Clin Immunol. 2019;143(3):970-977. doi:10.1016/j.jaci.2018.11.018 https://www.jacionline.org/article/S0091-6749(18)31720-2/fulltext
Creticos PS, Maloney J, Bernstein DI, et al. Randomized controlled trial of a ragweed allergy immunotherapy tablet in North American and European adults. J Allergy Clin Immunol. 2013;131(5):1342-9.e6. doi:10.1016/j.jaci.2013.03.019 https://www.jacionline.org/article/S0091-6749(13)00507-1/fulltext
Wang DH, Chen L, Cheng L, Li KN, Yuan H, Lu JH, Li H. Fast onset of action of sublingual immunotherapy in house dust mite-induced allergic rhinitis: a multicenter, randomized, double-blind, placebo-controlled trial. Laryngoscope. 2013 Jun;123(6):1334-40. doi: 10.1002/lary.23935. Epub 2013 Apr 24. PMID: 23616386.https://pubmed.ncbi.nlm.nih.gov/23616386/
Marogna M, Spadolini I, Massolo A, Canonica GW, Passalacqua G. Long-lasting effects of sublingual immunotherapy according to its duration: a 15-year prospective study. J Allergy Clin Immunol. 2010 Nov;126(5):969-75. doi: 10.1016/j.jaci.2010.08.030. Epub 2010 Oct 12. PMID: 20934206. https://www.jacionline.org/article/S0091-6749(10)01325-4/fulltext
Durham SR, Emminger W, Kapp A, de Monchy JG, Rak S, Scadding GK, Wurtzen PA, Andersen JS, Tholstrup B, Riis B, Dahl R. SQ-standardized sublingual grass immunotherapy: confirmation of disease modification 2 years after 3 years of treatment in a randomized trial. J Allergy Clin Immunol. 2012 Mar;129(3):717-725.e5. doi: 10.1016/j.jaci.2011.12.973. Epub 2012 Jan 29. PMID: 22285278. https://www.jacionline.org/article/S0091-6749(11)02942-3/fulltext